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Tirzepatide reduced airway inflammation and neutrophil aggregation in obese asthmatic mice by inhibiting the Notch signaling pathway, which in turn decreased the differentiation of Th17 cells
Claessens, M., Saris, W
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Tirzepatide, as highlighted in murine models, increases insulin sensitivity in a weight-dependent and weight-independent (through action on GIPR) manner, thereby stimulating metabolic pathways that oxidate glucose, lipids, and BCAAs
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